Product Overview
The Bruker SENTERRA II redefines user accessibility in confocal Raman microscopy by combining high-end spectroscopic performance with a high level of hardware automation. Designed for a "non-stop" analytical workflow, the system features a compact, integrated design where the spectrometer is built directly into the microscope stand. This efficiency allows users, from students to advanced researchers, to transition from sample visualization to high-quality Raman imaging with just a few clicks, making it an ideal platform for multi-user environments, failure analysis, and routine quality control.
At the heart of the SENTERRA II is a modular and intelligent architecture that adapts to diverse research needs. The system supports up to four internal excitation lasers, which can be switched instantly with automatic adjustment of filters and gratings to prevent configuration errors. Its modularity extends to specialized configurations, such as an inverted microscope for life science applications or the inclusion of an FT-Raman module to minimize background fluorescence in challenging samples. By integrating patented technologies like SureCal™ for permanent wavelength stability and Adaptive Chemical Imaging™ for automated data evaluation, the SENTERRA II ensures that scientists spend less time on recalibration and more time on high-impact discovery.
Product Demonstration
Key Features
- Full Hardware Automation: One-click switching of lasers, apertures, and gratings ensures an error-free and efficient workflow.
- Permanent Calibration: Features automated and continuous wavelength calibration, maintaining stability better than 0.02 cm⁻¹ for long-duration studies.
- High-Speed Confocal Imaging: Rapid data acquisition at speeds up to 260 spectra/sec, enabling the generation of high-resolution 2D and 3D Raman maps in seconds.
- Multi-Laser Versatility: Supports a wide range of excitation lines, including 488 nm, 532 nm, 633 nm, 785 nm, and 1064 nm.
- Research-Grade Resolution: Delivers spectral resolution down to 1.5 cm⁻¹ for demanding studies of polymorphism and crystallinity.
- Sub-Micron Precision: High-precision motorized stage with 50 nm step size achieves a lateral spatial resolution of < 0.5 µm.
- Intelligent Imaging Tools: Includes 3D Focus Fusion™ for clear imaging of uneven samples and Adaptive Chemical Imaging™ for automated chemical map generation.
- Validated Compliance: Fully compliant with GMP/cGMP and 21 CFR Part 11 requirements, with automated OQ/PQ test routines.
Specifications
| Laser Options | 488, 514.5, 532, 633, 785, 1064 nm |
| Spectral Resolution | Standard: < 4 cm⁻¹; High Resolution: < 1.5 cm⁻¹ |
| Wavelength Stability | < 0.02 cm⁻¹ (Short-term); < 0.1 cm⁻¹ (Long-term) |
| Spatial Resolution | < 0.5 µm (X/Y); < 2 µm (Z) |
| Imaging Speed | Up to 260 spectra/sec |