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Bruker Optics

LUMOS II ILIM

The LUMOS II ILIM is a high-speed chemical imaging solution that combines powerful Quantum Cascade Laser (QCL) technology with a widefield IR camera to deliver rapid, artifact-free analysis of biological tissues, pharmaceutical tablets, and particles.

Product Overview

The Bruker LUMOS II IR Laser Imaging Microscope (ILIM) redefines the standards of molecular imaging by integrating advanced laser technology into a fully automated platform. By combining an external cavity quantum cascade laser (QCL) with a room-temperature FPA microbolometer, the system achieves imaging speeds up to 169 times faster than conventional FT-IR scanning. This allows researchers to shift from analyzing individual spectra to viewing high-definition chemical images in real-time, providing unprecedented detail for expansive sample areas in minutes rather than days.

A core technical advantage of the LUMOS II ILIM is its patented hardware-based coherence reduction mechanism. This innovation ensures that chemical images are essentially free from laser-induced artifacts, resulting in sharp, high-contrast data across both transmission and reflection modes. The system is designed for high-throughput environments, featuring an open-access sample stage and WingGuard™ technology, which maintains a Laser Safety Class 1 rating without the need for bulky enclosures.

To streamline complex analytical tasks, the LUMOS II ILIM offers dedicated software workflows such as TissuePlus™ for spatial biology, TabletPlus™ for pharmaceutical deformulation, and ParticlePlus™ for microplastic and contaminant identification. These application-specific packages automate everything from measurement to AI-powered evaluation, making the instrument an essential tool for pathology labs, quality control, and advanced material research.

Product Demonstration

Key Features

  • Unrivaled Imaging Speed: Captures expansive chemical images at a rate of 4.5 mm² per second, significantly reducing time-to-result for large-scale studies.
  • Artifact-Free Imaging: Utilizes a patented coherence reduction method to provide sharp, clear chemical images without laser-typical interference patterns.
  • Cryogen-Free Operation: Equipped with a room-temperature FPA microbolometer, eliminating the need for liquid nitrogen and reducing operational complexity.
  • Highest Safety Standards: Features WingGuard™ technology to ensure a Laser Safety Class 1 environment while maintaining an open, user-friendly design.
  • Application-Specific Workflows: Includes dedicated "Plus" packages (Tissue, Tablet, Particle) that offer push-button analysis and AI-driven data evaluation.
  • Full Hardware Automation: Motorized X,Y,Z stages and automated calibration routines ensure maximum reproducibility and ease of use for all skill levels.
  • High Spatial Resolution: A specialized 4x refractive IR objective lens with a high numerical aperture (NA 0.6) provides a 4.25 µm\pixel size for detailed mapping.

Specifications

Light SourceExternal cavity quantum cascade laser (QCL)
DetectorRoom-temperature FPA microbolometer
Spectral Range950 – 1800 cm⁻¹
Spectral ResolutionDown to 2 cm⁻¹
Pixel Size4.25 µm/pixel
Imaging Speed4.5 mm²/second
Safety ClassLaser Safety Class 1 (via WingGuard™)

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