Vaya Handheld Raman – Raw Material Identity Verification System


The Vaya raw material identity verification system reduces the need for sampling, working through colored and opaque containers in pharmaceutical GMP quality control



The Agilent Vaya Raman handheld spectrometer increases raw material identity verification throughput without increasing costs by reducing the need for sampling. From clear glass vials to brown paper sacks, Vaya offers best-in-class testing through transparent containers, and transformative handheld testing through nontransparent containers – for the fastest possible release to manufacturing.

Vaya improves current testing protocols—from low volume sampling to 100% ID testing— and if regulators require more testing in future, you can move to a higher-throughput process without any additional equipment. The system combines conventional Raman with unique spatially offset Raman spectroscopy (SORS) for maximum sample/container compatibility. With a dedicated raw material identity testing workflow, Vaya is fast, fully compliant, easy to deploy and simple to use, requiring minimal training or operator skill.

How It Works

Deployment in the warehouse:

Vaya is designed for use in the quarantine area. The system automatically adapts the measurement mode to the container and contents—optimizing the Raman signal and measurement time for maximum testing speed and efficiency. Vaya delivers Pass/Fail answers in seconds, with easy integration in warehouse reception protocols through LIMS parsing and barcode scanning.

Developing methods for new materials:

Methods are developed by following intuitive wizard-based instructions. The user is guided through material and container spectroscopic evaluation, method development, and pharmacopeia-based identification method validation. Features like method assessment and spectral advisor allow users to develop robust methods by strengthening and challenging the method prior to deployment.


Vaya is operated using a simple LCD interface and a mechanical keypad with barcode scanner for quick and error-free data entry. The onboard software delivers clear and trusted answers using a dedicated raw material workflow supporting 21 CFR Part 11 compliance. With an embedded Wi-Fi adapter, Vaya can automatically connect to a corporate network for data synchronization and database backup.


  • Work smarter: ID through opaque containers in seconds. No sampling booth needed, minimum material handling
  • Compatible with most raw materials and containers: SORS technology verifies raw material identity without interference from the container or liner, minimizing fluorescence
  • Fast and robust to container variation: Vaya works faster than conventional handheld systems through transparent containers and handles opaque containers like white or colored tubs, FIBCs, papers bags, and amber bottles
  • Preserve container integrity: eliminate exposure to hazardous materials, maintain the shelf life of sterile contents, and prevent unnecessary waste
  • Easy to use: dedicated raw material ID workflow with clear Pass/Fail analysis and intuitive method development wizard, requires minimal training
  • GMP compliant: batch identification and method development with full audit trail, supports 21 CFR Part 11 compliance
  • Ready to deploy: LIMS-compatible data, 2D-barcode reader for fast data input/method selection and Wi-Fi for data synchronization


Specification Description
Dimensions Width: 127 mm
Height: 60 mm
Length: 257 mm (test piece fitted)
Technology SORS
Laser wavelength 830 nm
Laser power output Adjustable up to 450 mW (Class 3B)
Power Lithium-ion battery pack >4 hours operation time
Weight 1.62 kg
Barcode scanner Supports most 1D and 2D barcodes
Connectivity Wi-Fi
Ethernet (RJ-45 via Ethernet dongle)
Certification and compliance 21 CFR Part 11, USP <1120> and EP 2.2.48, USP<1225>, USP<1058>
Included accessories Two lithium-ion batteries; hand strap; shoulder strap; bottle adapters; vial holder; five vials; NIST-traceable system check test piece